Formulation and Evaluation of Antiacne Gel

Abstract

The creation and assessment of an herbal anti-acne gel utilizing natural plant extracts with antibacterial and anti-inflammatory qualities is the main goal of this study. Sebaceous gland irritation is the source of acne, a widespread dermatological disorder that is particularly prevalent in teenagers and young adults. Herbal components that are proven to be helpful against Propionibacterium acnes, including tulsi, tea tree oil, neem, and aloe vera, are used in the formulation of the gel. The produced gel was tested for stability, microbiological inhibition, pH, viscosity, spreadability, and skin irritation. The results showed high physicochemical stability and encouraging anti-acne efficacy. With fewer adverse effects, this formulation may provide a safer and more natural substitute for synthetic anti-acne drugs.

Introduction

Acne vulgaris is a common inflammatory skin condition affecting pilosebaceous units, caused by factors such as excessive sebum production, follicular hyperkeratinization, bacterial colonization (especially Cutibacterium acnes), and inflammation. While synthetic treatments exist, they often cause side effects like irritation and resistance, leading to increased interest in herbal alternatives.

Herbal anti-acne gels, favored for their non-greasy texture, ease of use, and controlled release of active ingredients, harness traditional medicinal plants such as neem, tulsi, turmeric, aloe vera, and tea tree oil. These plants offer antimicrobial, anti-inflammatory, antioxidant, and skin-soothing effects. Such formulations align with the global demand for natural, safe, and sustainable skincare products.

The study focuses on developing a stable, effective, and skin-friendly herbal anti-acne gel, evaluating its physicochemical properties, antimicrobial activity, and safety. Past research supports the efficacy of various herbal gels in reducing acne lesions, inflammation, and pigmentation with minimal side effects.

Challenges include standardizing herbal extracts, ensuring stability, regulatory approval, and consumer acceptance. Future directions point towards advanced delivery systems, clinical trials, combination therapies, product line expansion, and cosmeceutical branding.

Conclusion

A viable natural substitute for artificial acne treatments is the anti-acne herbal gel. The core causes of acne, including bacterial infection, excess sebum, and blocked pores, are addressed by the powerful antibacterial, anti-inflammatory, and antioxidant qualities of neem, tulsi, turmeric, aloe vera, and other herbs.The formulation\'s stability, safety, and effective spreadability were validated by evaluation experiments. Antimicrobial investigations showed strong effectiveness against bacteria that cause acne, and the pH was within the permissible skin range. The gel\'s exceptional skin compatibility was demonstrated by the absence of any negative skin responses.The growing popularity of skincare products devoid of chemicals and herbs confirms the study\'s applicability today. Additional developments in formulation methods and clinical testing can aid in overcoming some standardisation and stability-related obstacles. With the added advantage of nature\'s healing touch, this herbal anti-acne gel has great promise as a cosmeceutical solution for acne-prone people.

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Copyright

Copyright © 2025 Mr. Yash Memane, Ms. Pooja Gaikwad, Mr. Nitin Gawai, Mr. Prathamesh Divekar, Mr. Vivek Patil. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.