Authors: Sachin Laxman Ingale, Prof. Nakhate S. T. , Dr. Hingane L. D.
DOI Link: https://doi.org/10.22214/ijraset.2021.39701
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Herbal medicines Have been the basis of treatment and cure for various diseases and physiological conditions in traditional Methods of practice such as Unani, Ayurveda and Siddha. A large fraction of the world population, especially in The developing and underdeveloped countries still depends mainly on the traditional system of medicine. The use of plants and plant products in medicines is getting Popularized because the herbal medicines are cheap, easily available and have natural origin with higher safety Margins and lesser or no side effects. In Unani system of medicine Babool (Acacia Arabica) is considered as Plant having medicinal properties on various system of human body. Different parts of the plant including Bark, Root, gum, leaves, pod and seeds have medicinal properties. The present review is an attempt to highlight the Various ethnobotanical and Unani traditional uses as well as phytochemical and pharmacological reports on Acacia arabica to which commonly known as Babool.
I. INTRODUCTION
Use of herbal medicines in Asia represents a Long history of human interactions with the environment. The Medicinal value of plants lies in some chemical substances that Produce a definite physiological action on the human body.Acacia is the most significant genus of family: Leguminosae, first of All described by Linnaeus in 1773.
IS estimated that there are Roughly 1380 species of Acacia worldwide.2 Acacia species—Commonly known as Babool (or babul), Egyptian mimosa, Egyptian Thorn, kikar, Indian gum, and red thorn—have long been used for The treatment of various ailments Dioscorides, the Greek physician Considered to be the father of botany, named it akacia, and it is From this word that the modern name, acacia, is derived. The origin Of the word, acacia, is ?spiny,? which is a typical feature of the Species.
A. Advantages Of Paste
B. Disadvantages of Past
C. Ideal Characteristics Of Paste
It consists of fatty base like petroleum jelly, at least 25% solid substance.
II. HISTORY OF PLANT
Known as Vachellia Nilotica, the Babul Tree is in the Fabaceae or Leguminosae family, which basically means that the tree belongs to the legume, bean or pea family.
A. Taxonomical Classification
B. Morphology
It is a moderate-sized, almost evergreen tree with a short trunk, and a spreading crown. The bark is dark brown to almost black, longitudinally fissured or deeply cracked. Leaves are 2-pinnate and the main rachis has glands. Stipular spines are variable.
Leaflet are subsessile and glabrous. Flowers golden-yellow, fragrant, crowded in long-stalked globose heads, forming auxiliary clusters of 2-5 heads. Pods are stalked, flat, compressed 7.5-15.0 cm in length and contracted between the circular seeds. Three subspecies are recognized in India.
C. Phytochemical
2. Gum: Gum contains galactose, L-rhamnose, L-arabinose and four Aldobiouronic acids.
3. Fruit: It contains a high percentage of phenolic constituents Consisting of m-digallic acid, gallic acid, its methyl and ethyl esters.
4. Flower: It contains if stearic acids.
D. Pharmacological Activitie
2. Leaves: Infusion of tender leaves used as an astringent and Remedy for diarrhoea and dysentery. 18, 19, 20, 28, 32 Also it is used in Headaches, eczema, abscess, ophthalmic disorders, 20, 23 in throat Infection, urinary problems gonorrhoea.
3. Flowers: Flowers are useful in reducing the body Temperature, ear ache and as a tonic, antidiarrheal, antidysenteric.
4. Roots: Used for wound healing and burning sensation.
5. Extract: It is an astringent and injected to allay irritation in Acute gonorrhoea and leucorrhoea.
III. REQUIREMENTS
Extracted gums, Water, Mineral oils like liquid paraffin,, Waxes and foaming Agent Like Coco glucoside, perfuming agent like ethyl alcohol and glycerine base solution etc.
INGREDIENTS |
QUANTITY TAKEN |
Extracted gums |
12 gram |
Water |
5ml |
Liquid paraffin |
3ml |
Coco glucoside |
3ml |
Glycerine base solution |
5ml |
Ethyl alcohol |
3ml |
A. Wound & Wound healing Process
a. Closed Wound: Closed fracture.
b. Open Wound: Crash wound , bite wound and burn wound.
B. Paste
C. Methods of Preparation
They are divided into two types:
First step oil in water (o/w) this method is used to in this procedure.
IV. PROCEDURE
A. Dosage Form
B. Formulation Formula
Name of the preparation |
Active Ingredients |
Quantity Taken |
Use |
Preparation of babool gum paste. |
Glycerine base solution |
5ml |
Wound healing , skin disease and burn injury etc. |
|
|
|
|
|
Ethyl alcohol |
3ml |
|
|
|
|
|
|
Liquid paraffin |
3ml |
|
|
|
|
|
|
Water |
5ml |
|
|
|
|
|
|
Extracted gums |
12 gms |
|
|
|
|
|
|
Coco glucoside |
3ml |
|
C. Evaluation Parameters of Paste
To establish the quality of preparation we are perform following physico-chemical parameters.
S= m*l/t
Where, m = weight applied to upper slide.
L = length moved on the glass slide.
T = time taken.
4. Saponification Value: 2gm of substance refluxed with 25ml of 0.5 N alcoholic KOH for 30min, to this 1ml of phenolphthalein added and titrated immediately, with 0.5N HCl, note the reading as ‘a’. Repeat the operation omitting the substance being examined. Note the reading as ‘b’. Saponification value = (b-a)*28.05/w
Where, w = weight of substance in gram.
5. Acid Value: 10gm of substance is dissolved in accurately weighed 50ml mixture of equal volume of alcohol and solvent ether, the flask was connected to reflux condenser and slowly heated, until sample was Dissolved completely, to this 1ml of phenolphthalein added and titrated with 0.1N NaOH, until faintly pink colour appears after shaking for 30 seconds. Acid
Value = n*5.61/w
Where,
N = the no. of ml of 0.1 N KOH solution.
W = the weight of substance in gram.
6. Viscosity: Viscosity of formulated creams can be determined by using Brookfield Viscometer.
7. Homogeneity: The formulation was tested for the homogeneity by visual appearance and by touch.
8. Removal: Ease of removal of the creams applied was examined by washing the applied part with tap water.
9. Dye Test: Scarlet dye is mixed with the cream. Place a drop of cream in a slide and cover with a cover slip and examine it under a microscope. If the disperse globule appears red and the ground colourless then it is o/w type and the reverse condition appears in w/o type of creams.
V. RESULT
Formulation of Herbal wound healing paste from babool tree was prepared successful.
As the pharmacologists are looking forward to develop new drugs From natural sources, development of modern drugs from Acacia Arabica can be emphasized for the control of various diseases. It Contains a number of phytoconstituents, which are the key factors In the medicinal value of this plant. It is quite evident from this Review that Acacia arabica is an important medicinal herb and Extensively all types of medicinal systems.
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Copyright © 2022 Sachin Laxman Ingale, Prof. Nakhate S. T. , Dr. Hingane L. D.. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Paper Id : IJRASET39701
Publish Date : 2021-12-29
ISSN : 2321-9653
Publisher Name : IJRASET
DOI Link : Click Here