Formulation and Evaluation Poly Herbal Cream to Treat Skin Burning

Abstract

This study focuses on the formulation and evaluation of a polyherbal cream intended for the treatment of minor skin burns, incorporating natural ingredients such as Delonix regia extract, turmeric (Curcuma longa), peppermint oil, lavender oil, and honey. Each component was selected based on its well-documented medicinal properties: Delonix regia for its anti-inflammatory and antioxidant activities; turmeric for its curcumin content, known for wound healing and antimicrobial effects; peppermint oil for its soothing, cooling action; lavender oil for its analgesic and skin regenerative capabilities; and honey for its antibacterial and moisturizing benefits. The ingredients were homogenously mixed into a cream base and subjected to physicochemical evaluation, including pH, viscosity, spreadability, and stability testing. The formulated polyherbal cream was then evaluated for its efficacy on minor thermal burns using in vitro and ex vivo models. Results demonstrated that the cream exhibited significant wound healing properties, reduced inflammation, and improved epithelial regeneration compared to the control. The presence of both essential oils and botanical extracts contributed synergistically to the therapeutic action, making the polyherbal formulation a promising, natural alternative for managing mild to moderate burn injuries. Further clinical testing is suggested to validate its safety and efficacy in human subjects.

Introduction

Skin burns, caused by heat, chemicals, or other factors, vary in severity from first to third degree, with deeper burns requiring more intensive treatment. Traditional synthetic burn treatments like silver sulfadiazine may delay healing or cause side effects, prompting interest in natural herbal remedies with anti-inflammatory, antimicrobial, and healing properties.

This study developed a polyherbal cream combining extracts from Delonix regia, turmeric (Curcuma longa), peppermint oil, lavender oil, and honey. These ingredients are chosen for their pain relief, anti-inflammatory, soothing, and wound-healing effects. The cream formulation also includes beeswax, borax, preservatives, and water to create a stable topical product.

The preparation involves drying and powdering plant materials, solvent extraction, mixing with oils and waxes, and adding preservatives. Chemical tests confirmed the presence of bioactive compounds like flavonoids and terpenoids. The cream was evaluated for physical properties, pH, spreadability, washability, irritancy (non-irritant), and stability (no phase separation), showing a smooth, semisolid, light-yellow product with an unpleasant odor.

Conclusion

The present study focused on the formulation and evaluation of a poly herbal cream incorporating delonix regia , tumaric, honey,lavender oil,and peppermint oil for the treatment of skin burns. Each ingredient was selected based on its known pharmacological properties; delonix regia for its anti inflammatory an wound healing potential, tumaric for its antioxidant and antimicrobial effects , honey for its natural soothing and tissue regenerating action, and the essential oils for their analgesic, cooling and antiseptic effects. The synergistic combination og these ingredients aimed to accelerate the healing process, reduce inflammation, and protect the damaged skin infection.

References

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Copyright

Copyright © 2025 Sonali Prabhakar Jadhav, Gauri Shivkumar Kashte, Abhijeet Rajesh Pohankar, Ritesh Ambadas Rathod, Prof. Mirza Nazish Baig. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.