Therapeutic Potential of Jasmine Herbal Lozenges in the Treatment of Recurrent Aphthous Stomatitis

Abstract

Mouth ulcers, also known as aphthous ulcers, are common inflammatory lesions that affect the mucous membranes of the oral cavity. They can cause significant discomfort, pain, and difficulty in eating, drinking, and speaking. Conventional treatments, such as topical corticosteroids and antiseptic gels, often provide temporary relief and may have undesirable side effects. In response to the growing demand for safe and effective natural remedies, this study focuses on the formulation and evaluation of herbal lozenges containing Jasminum sambac (jasmine) extract for the treatment of mouth ulcers. Jasminum sambac is traditionally known for its anti-inflammatory, analgesic, antimicrobial, and soothing properties, making it a suitable candidate for oral ulcer therapy. The lozenges were prepared using a traditional candy base, ensuring a slow and sustained release of active herbal ingredients, allowing direct and prolonged contact with the ulcerated area in the mouth. The formulated lozenges were evaluated for various physicochemical parameters including hardness, uniformity of weight, friability, pH, and disintegration time. Phytochemical screening confirmed the presence of bioactive constituents such as flavonoids, tannins, and alkaloids that contribute to the therapeutic action. The results suggest that the herbal jasmine lozenges are not only effective in treating mouth ulcers but are also stable, palatable, and safe for oral use. The lozenge form offers convenience, accurate dosing, and prolonged action, which can improve user adherence and therapeutic outcomes. Given the increasing preference for herbal and natural treatments, this formulation presents a viable alternative to synthetic oral ulcer therapies. In conclusion, herbal jasmine lozenges are a promising natural solution for mouth ulcer treatment, offering a blend of traditional herbal benefits and modern pharmaceutical convenience.

Introduction

Jasmine (genus Jasminum) is a group of over 200 species of shrubs and vines known for their fragrant flowers, primarily white, yellow, or pink. Native to tropical and subtropical Eurasia, Australasia, and the Himalayas, jasmine plants belong to the Oleaceae family and thrive in warm climates. They have cultural significance in many countries, symbolizing love, purity, and beauty, and are widely used in perfumery, aromatherapy, and traditional medicine.

Jasminum sambac (Arabian jasmine) is notable for its essential oils with calming, anti-inflammatory, antioxidant, and antimicrobial properties. The plant contains alkaloids, flavonoids, volatile oils, and other bioactive compounds that contribute to its medicinal effects.

Jasmine is used in various forms, including essential oils, perfumes, and herbal teas, and has traditional uses for treating headaches, skin conditions, digestive issues, and mouth ulcers. In particular, jasmine extracts are formulated into lozenges for oral administration to treat mouth ulcers by reducing pain, inflammation, and promoting healing.

Mouth ulcers are painful lesions in the mouth caused by trauma, nutritional deficiencies, infections, stress, or autoimmune diseases. Treatment typically involves topical agents to soothe pain and promote healing. The jasmine lozenges work through anti-inflammatory, antioxidant, antimicrobial, astringent, and analgesic mechanisms.

The text also outlines the preparation of jasmine leaf extract, formulation of herbal lozenges incorporating jasmine extract, and the evaluation of their physical and chemical properties for anti-ulcer activity.

Conclusion

The development of herbal jasmine lozenges represents a promising natural approach for the effective management of mouth ulcers. Mouth ulcers are a common oral health issue that cause pain, discomfort, and difficulty in speaking and eating. Conventional treatments often involve chemical-based topical applications, which may have side effects and limited patient compliance. In this study, Jasminum sambac (jasmine) extract was selected as the primary active ingredient due to its well-documented anti-inflammatory, antimicrobial, and analgesic properties. Its incorporation into a lozenge form allows for direct and prolonged contact with the oral mucosa, which enhances its local therapeutic effects. In conclusion, hard herbal jasmine lozenges serve as a convenient, effective, and safe alternative to conventional treatments for mouth ulcers. Their natural composition makes them suitable for a wide range of users, including those seeking herbal remedies. With further clinical validation, these lozenges could become a widely accepted product in the field of oral healthcare and herbal therapeutics.

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Copyright

Copyright © 2025 Sanika Sanjay Gondkar, Mr. Kiran Waghmare, Dr Gaffar Sayyed, Dr. Sanjay Garje, Shri Amolak Jain. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.